Fig 1: Sevoflurane exposure induced cognitive impairment and suppressed Hsp70 protein levels in aged mice. (a–d) Spatial learning and memory of aged mice were determined by the Morris water maze. Escape latencies (a) and average speed of swimming (b) were recorded in the three training sessions. The duration in the target quadrant (c) and the number of times crossing the platform site during the probe trial were recorded. The Hsp70 concentrations in plasma (e) and (f) were determined in mice at 48 h after sevoflurane anesthesia with different concentrations for 3 h. Twelve mice were used for each group. Data were represented by mean ± SD. *p < .05, **p < .01, ***p < .001
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